Performance of metagenomic next-generation sequencing for microbiological diagnosis of infectious uveitis.

ABSTRACT: Introduction. Diagnosis of uveitis is challenging due to the multitude of possible pathogenies. Identifying infectious and non-infectious uveitis is of great clinical significance. Recently, metagenomic next-generation sequencing (mNGS) was used to detect infectious and non-infectious uveitis, but its efficacy has not been widely evaluated.Hypothesis. Compared with routine diagnostic tests (RDTs), mNGS is more effective in identifying infectious and non-infectious uveitis.Aim. To describe the microbiological diagnostic performance of mNGS in detecting infectious and non-infectious uveitis.Methodology. Patients with suspected infectious uveitis of uncertain pathogenesis were tested by mNGS and RDTs. Infectious and non-infectious uveitis were grouped according to

SUBMITTER: Cai Z 

PROVIDER: S-EPMC11633842 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature