Coagulation Risk Predicting in Anticoagulant-Free Continuous Renal Replacement Therapy.

ABSTRACT:

Introduction

Continuous renal replacement therapy (CRRT) is a prolonged continuous extracorporeal blood purification therapy to replace impaired renal function. Typically, CRRT therapy requires routine anticoagulation, but for patients at risk of bleeding and with contraindications to sodium citrate, anticoagulant-free dialysis therapy is necessary. However, this approach increases the risk of CRRT circuit coagulation, leading to treatment interruption and increased resource consumption. In this study, we utilized artificial intelligence machine learning methods to predict the risk of CRRT circuit coagulation based on pre-CRRT treatment metrics.

Methods

We retrospectively analyzed 212 patients who underwent anticoagulant-free CRRT from October 2022 to October 2023. Patients

SUBMITTER: Liu L 

PROVIDER: S-EPMC11633885 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature