Dyslipidemia in severe fever with thrombocytopenia syndrome patients: A retrospective cohort study.

ABSTRACT:

Background

Severe fever with thrombocytopenia syndrome (SFTS) is a rapidly progressive infectious disease triggered by a novel bunyavirus (SFTSV). Despite the critical role of host lipid metabolism in viral infections, research on dyslipidemia in SFTS remains limited.

Methods

This retrospective study included 433 SFTS patients, who were stratified into survival group (n = 365) and death group (n = 68) and who were treated at the Shandong Public Health Clinical Center from September 2021 to December 2023. Additionally, 96 healthy controls with matching baseline characteristics were included from Shandong Provincial Hospital. Cross-sectional analysis based on admission data and longitudinal analysis over time were employed to survey the correlation between serum lipid profiles

SUBMITTER: Guo S 

PROVIDER: S-EPMC11634008 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature