Pharyngeal neuronal mechanisms governing sour taste perception in <i>Drosophila melanogaster</i>.

ABSTRACT: Sour taste, which is elicited by low pH, may serve to help animals distinguish appetitive from potentially harmful food sources. In all species studied to date, the attractiveness of oral acids is contingent on concentration. Many carboxylic acids are attractive at ecologically relevant concentrations but become aversive beyond some maximal concentration. Recent work found that Drosophila ionotropic receptors IR25a and IR76b expressed by sweet-responsive gustatory receptor neurons (GRNs) in the labellum, a peripheral gustatory organ, mediate appetitive feeding behaviors toward dilute carboxylic acids. Here, we disclose the existence of pharyngeal sensors in Drosophila melanogaster that detect ingested carboxylic acids and are also involved in the appetitive responses to carbo

SUBMITTER: Shrestha B 

PROVIDER: S-EPMC11634064 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature