Safety and efficacy of stem cell therapy for Crohn's disease: An umbrella review of systematic reviews.

ABSTRACT:

Background

Crohn's disease is a chronic, relapsing form of inflammatory bowel disease marked by severe gastrointestinal inflammation and a broad range of debilitating symptoms. Despite advances in medical treatments, achieving sustained remission remains challenging for many patients. This umbrella review aims to consolidate evidence from various systematic reviews to evaluate the efficacy and safety of stem cell therapies in treating Crohn's disease.

Methods

This review followed the Joanna Briggs Institute methodology and adhered to PRISMA guidelines. A literature search of PubMed, Web of Science, Embase, and the Cochrane Library covered records up to April 20, 2024. Only systematic reviews and meta-analyses on stem cell therapy for Crohn's disease were considered. Data wer

SUBMITTER: Thangavelu L 

PROVIDER: S-EPMC11634090 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature