WQFM-DISCO: DISCO-enabled wQFM improves phylogenomic analyses despite the presence of paralogs.

ABSTRACT:

Motivation

Gene trees often differ from the species trees that contain them due to various factors, including incomplete lineage sorting (ILS) and gene duplication and loss (GDL). Several highly accurate species tree estimation methods have been introduced to explicitly address ILS, including ASTRAL, a widely used statistically consistent method, and wQFM, a quartet amalgamation approach experimentally shown to be more accurate than ASTRAL. Two recent advancements, ASTRAL-Pro and DISCO, have emerged in phylogenomics to consider GDL. ASTRAL-Pro introduces a refined quartet similarity measure, accounting for orthology and paralogy. On the other hand, DISCO offers a general strategy to decompose multi-copy gene trees into a collection of single-copy trees, allowing the utilization of

SUBMITTER: Hakim SA 

PROVIDER: S-EPMC11634537 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature