Herbal placebo response in clinical trials on irritable bowel syndrome: a systematic review and meta-analysis.

ABSTRACT:

Aim of the study

To systematically evaluate the herbal placebo response in randomized controlled trials (RCTs) of herbal medicine on irritable bowel syndrome (IBS).

Materials and methods

We searched for RCTs with herbal placebo groups for IBS in PubMed, EMBASE, the Cochrane Library, the China National Knowledge Infrastructure (CNKI), the Wan Fang database and Sinomed database from 31 January 1994 to November 2023, and the quality of the literature was evaluated by the Cochrane risk of bias assessment criteria. The primary outcome indicators were response rate, abdominal pain and stool improvement rate, which were analyzed by single-group rate meta-analysis. Secondary outcomes were analyzed in subgroups based on diagnostic criteria, duration of treatment, subtype, research lo

SUBMITTER: Huang K 

PROVIDER: S-EPMC11634590 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature