The frequency and clinical associations of opioid use in systemic sclerosis.

ABSTRACT:

Objective

To define the frequency and associations of opioid use in SSc.

Methods

Australian Scleroderma Cohort Study participants meeting ACR/EULAR criteria for SSc were included. Current or previous opioid use was recorded at each visit, with long-term use defined as use on two or more consecutive visits. Groups were compared using two-sample t-test, Wilcoxon rank sum test or chi-squared test. Generalised estimating equations were used to model longitudinal data.

Results

Of 1951 participants with a mean age of 46.7 years (s.d. 14.4), 88% were female and 12% had ever received any opioids since SSc onset. Of these, 46% recorded opioid use across multiple consecutive study visits. Digital ulcers (63% vs 52%), synovitis (57% vs 38%), interstitial lun

SUBMITTER: Fairley JL 

PROVIDER: S-EPMC11634672 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature