Comparative analysis of antimicrobial resistance and genetic diversity of Bordetella bronchiseptica isolates obtained from swine within the United States.

ABSTRACT:

Introduction

Bordetella bronchiseptica is bacterial pathogen that is pervasive in swine populations and serves multiple roles in respiratory disease.

Methods

This study utilized whole-genome sequencing (WGS) analysis to assess the sequence type (ST), identify the genetic diversity of genes predicted to encode regulatory and virulence factors, and evaluated any potential antimicrobial resistance harbored by B. bronchiseptica isolates obtained from swine within the U.S.

Results

While a generally high degree of genomic conservation was observed among the swine B. bronchiseptica isolates, genetic diversity was identified within the fimNX locus and among the sequence type six (ST6) isolates. The majority of B. bronchiseptica isolates exhi

SUBMITTER: Nicholson TL 

PROVIDER: S-EPMC11634850 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature