Association between urinary cadmium levels and prevalence of coronary artery disease: NHANES cross-sectional study (2009-2018).

ABSTRACT:

Objective

This study aims to sheds light on the correlation between urinary cadmium (Cd-U) exposure and coronary heart disease (CHD) and the mediating effects of serum alkaline phosphatase (ALP) based on a sample of adults in the United States.

Methods

A comprehensive cross-sectional study was performed on 8,998 CHD participants who participated in the National Health and Nutrition Examination Survey (NHANES) from 2009 to 2018. Weighted logistic regression was employed to elucidate the association between Cd-U and the likelihood of CHD. We investigated the link of Cd-U exposure to the prevalence of CHD using limited cubic spline models to analyze the exposure-dose relationship. In addition, mediation analyses were conducted to explore the role of serum ALP in metal exposure-

SUBMITTER: Ma X 

PROVIDER: S-EPMC11634864 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature