Altered gut microbiome in convalescent patients with coronavirus disease 2019.

ABSTRACT:

Introduction

Coronavirus disease 2019 (COVID-19) alters the gut microbiome. This study aimed to assess the association between the disease severity of COVID-19 and changes in stool microbes through a seven-month follow-up of stool collection.

Methods

We conducted a multicentre, prospective longitudinal study of 58 COVID-19 patients and 116 uninfected controls. Differences in the gut microbiota were analysed using 16S ribosomal RNA sequencing. The first stool samples were collected at an early convalescent phase of COVID-19, and the second sample was collected at least seven months after COVID-19 infection.

Results and discussion

At the order level, Eubacteriales and Bifidobacteriales decreased, while Bacteroidales and Burkholderiales increa

SUBMITTER: Lee KH 

PROVIDER: S-EPMC11634865 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature