Bread Consumption and Cancer Risk: Systematic Review and Meta-Analysis of Prospective Cohort Studies.

ABSTRACT: Because bread can contain potential carcinogens such as acrylamide, and is widely consumed, we conducted a systematic review and meta-analysis to determine whether bread consumption is associated with increased cancer risk. PubMed and Medline databases were searched up to 1 March 2024, for studies that provided hazard ratios (HRs) (or similar) for bread consumption and cancer incidence or mortality. Only prospective cohort studies were included. We used the Preferred Reporting Items of Systematic reviews and Meta-Analyses checklist. Meta-analysis was performed with Cochrane's RevMan 5.4.1 software using a DerSimonian-Laird random-effects model. Heterogeneity was assessed with Cochrane's Q (χ²) and I ² statistics, and publication bias was assessed with Eg

SUBMITTER: Gaesser GA 

PROVIDER: S-EPMC11634998 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature