Development and validation of a nomogram for incorporating ¹⁸F-FDG PET/CT spleen uptake for predicting prognosis in elderly esophageal cancer patients treated with radiotherapy.

ABSTRACT:

Background

There is currently no widely accepted prognostic model specifically for elderly patients with esophageal squamous cell carcinoma (ESCC) undergoing radiotherapy. This study aimed to develop a nomogram incorporating metabolic imaging parameters from ¹⁸F-fluorodeoxyglucose positron emission tomography-computed tomography (¹⁸F-FDG PET/CT) to predict overall survival (OS) in this patient population. The clinical need for such a prediction model is significant given the challenges of treatment planning in elderly patients with ESCC undergoing radiotherapy.

Methods

A retrospective analysis was conducted on 118 elderly patients with ESCC treated with radiotherapy. The patients were evaluated using ¹⁸F-FDG PET/CT imaging prior to treatment,

SUBMITTER: Liu D 

PROVIDER: S-EPMC11635226 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature