The establishment of an <i>ex vivo</i> lung perfusion rat model: insights from Jiangxi, China.

ABSTRACT: The scarcity of viable donor lungs is a formidable obstacle in lung transplantation (LTx) surgery. This issue significantly hinders the availability of this life-saving procedure for patients in need. To alleviate this shortage, researchers have turned to ex vivo lung perfusion (EVLP) technology as a means to evaluate and potentially repair marginal donor lungs, thereby increasing the donor pool and improving access to transplantation. However, it is important to note that the current capabilities of EVLP technology are still somewhat limited, and further research, development, and optimization are necessary to maximize its potential. To advance this field of study, animal experiments play a crucial role in providing a controlled environment for exploring the possibilities and limitations

SUBMITTER: Zou G 

PROVIDER: S-EPMC11635235 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature