Prognostic impact of <i>EGFR</i> mutations in T1-4N0M0 lung adenocarcinoma: analyses focus on imaging and pathological features.

ABSTRACT:

Background

With the development of tyrosine kinase inhibitor (TKI) treatment, the prognosis of advanced lung adenocarcinoma (LUAD) patients with epidermal growth factor receptor (EGFR) mutations has been continuously improving. This study aims to propose the utilization of pathological characteristics and imaging features to evaluate the impact of EGFR gene mutations on the prognosis of T1-4N0M0 LUAD.

Methods

Among the cases diagnosed with LUAD between April 2015 and April 2016, 438 patients with T1-4N0M0 LUAD were included, and the clinical characteristics were collected. EGFR mutations were analyzed in these patients who underwent lobectomy with different radiological and pathological types for the relation to patient prognosis.

Results

Patients

SUBMITTER: Chen JY 

PROVIDER: S-EPMC11635242 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature