Prescribing patterns in older people with advanced chronic kidney disease towards the end of life.

ABSTRACT:

Background

Advancing age and chronic kidney disease (CKD) are risk factors for polypharmacy. Polypharmacy is associated with negative healthcare outcomes. Deprescribing, the systematic rationalization of potentially inappropriate medications, is a proposed way of addressing polypharmacy. The aim of this study was to describe longitudinal prescribing patterns of oral medications in a cohort of older people with advanced CKD in their last years of life.

Methods

The European QUALity (EQUAL) study is a European, prospective cohort study of people ≥65 years with an incident estimated glomerular filtration rate (eGFR) of ≤20 mL/min/1.73 m². We analysed a decedent subcohort, using generalized additive models to explore trends in the number and types of prescribed oral me

SUBMITTER: Letts M 

PROVIDER: S-EPMC11635369 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature