Synthesis, Characterization, and BSA Binding Properties of Carboxylated Merocyanine-Based Fluorophores.

ABSTRACT: This study describes the synthesis of new carboxylated merocyanine dyes by Knoevenagel condensation between 4-carboxybenzaldehyde and indolium/benzoindolium- and benzothiazolium-based coupling compounds. The condensations were performed in the presence of ammonium acetate, and the products were obtained in good yields after simple purification. These merocyanines exhibit UV-A-to-blue absorption and blue-to-green fluorescence emission, characterized by relatively large Stokes shift values (∼5000 cm^-1). In addition, quantum chemical calculations were conducted to better explore the electronic and photophysical properties of the merocyanines under study. Thermal analysis via thermogravimetric analysis (TGA) revealed distinct decomposition stages for the merocyanines, with stability

SUBMITTER: Duarte RC 

PROVIDER: S-EPMC11635679 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature