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Surgical outcomes of profunda artery perforator flap in head and neck reconstruction: A systematic review and meta-analysis.


ABSTRACT:

Objective

This study aims to evaluate the efficacy of the profunda artery perforator (PAP) flap in head and neck reconstruction.

Methods

A single arm meta-analysis was performed for flap survival rate (primary outcome), reoperation for major complication, and overall complication rates (secondary outcomes).

Results

The search strategy yielded a total of 295 potentially relevant publications, of which 13 were included. A total of 305 patients (males: 80.8%, n = 232/281), with a median age of 56.1 years (n = 305/305; 95% CI 53.9-63), who underwent a total of 307 PAP flap reconstructions for head and neck defects were included. Flap survival rate was 100% (n = 306/307; 95% CI 99.6%-100%), with a reoperation rate for major complications of 3.7% (n = 15/307; 95% CI 1.85%-6

SUBMITTER: Marchi F 

PROVIDER: S-EPMC11635749 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature