Performance of a score to characterise adequate contact among the social network of persons with TB.

ABSTRACT:

Background

Transmission of Mycobacterium tuberculosis requires adequate contact between an infectious case and a susceptible host. The aim of this analysis was to validate a recently developed contact score that assessed settings of exposure and relationships between the case and contact.

Methods

In a cross-sectional study from Kampala, Uganda, we estimated the prevalence of tuberculous infection (TBI) in social contacts of adult TB cases according to the setting and relationship domains of the contact score. We calculated the prevalence ratio (PR) for the association between contact scores (by domain) with TBI using modified Poisson regression models.

Results

We enrolled 955 household and community contacts from 119 TB cases. The prevalence of TBI in the socia

SUBMITTER: Castellanos ME 

PROVIDER: S-EPMC11636496 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature