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Magnetic nanoparticles in square-wave fields for breakthrough performance in hyperthermia and magnetic particle imaging.


ABSTRACT: Driving immobilized, single-domain magnetic nanoparticles at high frequency by square wave fields instead of sinusoidal waveforms leads to qualitative and quantitative improvements in their performance both as point-like heat sources for magnetic hyperthermia and as sensing elements in frequency-resolved techniques such as magnetic particle imaging and magnetic particle spectroscopy. The time evolution and the frequency spectrum of the cyclic magnetization of magnetite nanoparticles with random easy axes are obtained by means of a rate-equation method able to describe time-dependent effects for the particle sizes and frequencies of interest in most applications to biomedicine. In the presence of a high-frequency square-wave field, the rate equations are shown to admit an analytical solutio

SUBMITTER: Barrera G 

PROVIDER: S-EPMC11636937 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature