AN OXIDATIVE DEAROMATIZATION CYCLIZATION MODEL FOR CORTISTATIN A.

ABSTRACT: The feasibility of a hypervalent iodine-mediated oxidative dearomatization/cyclization to produce the oxabicyclo[3.2.1]octene of cortistatin A has been demonstrated through a model study. An interesting tandem cyclization via a Ritter intermediate has been observed when a slightly different substrate was used.

SUBMITTER: Dai M 

PROVIDER: S-EPMC11636941 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature