Sepsis mimics among presumed sepsis patients at intensive care admission: a retrospective observational study.

ABSTRACT:

Background

Diagnosing sepsis remains a challenge because of the lack of gold-standard diagnostics. Since there are no simple, broadly accepted criteria for infection, there is a risk of misclassifying sepsis patients (sepsis mimics) among patients with organ failure. The main objective of this study was to investigate the proportion of non-infected patients (sepsis mimics) in ICU patients with presumed sepsis at intensive care unit (ICU) admission.

Methods

Adult patients were screened retrospectively during 3.5 years in four ICUs in Sweden for fulfilment of the sepsis-3 criteria at ICU admission (presumed sepsis). Proxy criteria for suspected infection were sampled blood culture(s) and concomitant antibiotic administration. Culture-negative presumed sepsis patients were scre

SUBMITTER: Lengquist M 

PROVIDER: S-EPMC11636973 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature