Cognition and behavior in adults with neurofibromatosis type 1.

ABSTRACT:

Background

Neurofibromatosis Type 1 (NF1) is a congenital neurocutaneous disorder. As NF1 is incurable and presents with a wide range of physical and mental symptoms, knowledge of neurocognitive and behavioral functioning can be an important aid in understanding their functional impact, and developing treatment options. To date, studies in children with NF1 have shown dysfunction in several domains, but much less is known about cognition and behavior in adults with NF1. The present study describes the neuropsychological phenotype of adults with NF1 based on comprehensive clinical examination of cognition and behavior across multiple functions.

Methods

Participants were 62 adults with NF1 (mean age 38.2 years; SD 13.4). All underwent individual clinical neuropsychologi

SUBMITTER: Bos-Roubos A 

PROVIDER: S-EPMC11638057 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature