Whole mitochondrial genome analyses of Han population from Shandong of China using massively parallel sequencing.

ABSTRACT:

Introduction

Mitochondrial DNA (mtDNA) has been extensively utilized in archeology, human evolutionary genetics, and forensic genetic for over three decades, primarily due to its maternal inheritance and relatively high mutation rate. The Chinese Han, the largest and most widely distributed ethnic group in China, have been the focus of numerous genetic studies. However, the forensic parameters and genetic structure of the Shandong Han, specifically in relation to the whole mitochondrial genome, remain undocumented.

Methods

We performed whole mitochondrial genome sequencing on 141 unrelated Han individuals from Shandong province using massively parallel sequencing.

Results

A total of 135 unique mtDNA haplotypes were identified, classified into 105 haplogroups, resultin

SUBMITTER: Zhang J 

PROVIDER: S-EPMC11638193 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature