Non-linear relationship between platelet count and 28-day mortality in critically ill patients with infective endocarditis: a retrospective cohort study from MIMIC IV database.

ABSTRACT:

Background

The relationship between platelet count and 28-day mortality in critically ill patients with infective endocarditis (IE) is currently not well established.

Objective

This study aims to investigate the impact of platelet count on 28-day mortality in critically ill patients with infective endocarditis.

Methods

A retrospective cohort study was conducted involving 450 participants diagnosed with infective endocarditis and admitted to intensive care units (ICU). Vital signs, laboratory parameters and comorbidity were collected for all participants to analyze the association between platelet count and 28-day mortality. In order to assess the independent association between platelet count and 28-day mortality, we employed multivariable cox hazard regression analys

SUBMITTER: Huang Y 

PROVIDER: S-EPMC11638226 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature