Predictors of Enrollment and Adherence in a Randomized Tobacco Cessation Clinical Trial.

ABSTRACT:

Background

New therapeutic cessation approaches are being tested in clinical trials to engage and retain people who smoke. Our team is conducting a pragmatic randomized clinical trial (RCT) to evaluate a new treatment for tobacco dependence, but enrolling participants and ensuring adherence has been more challenging than in previous trials.

Objective

To determine the predictors of enrollment and adherence in the RCT.

Design

A secondary analysis of data from a tobacco cessation RCT.

Methods

Data was collected during a two-group RCT testing the efficacy of an integrative guided imagery vs behavioral treatment, with both conditions involving six weekly, hour-long sessions over 9 weeks.

Results

Of the 1074 randomized participants, 803 (74.8%) enrolled (compl

SUBMITTER: Coffee Z 

PROVIDER: S-EPMC11638983 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature