Phytochemical, pharmacological, pharmacokinetic and toxicological characteristics of <i>Ziziphi Spinosae Semen</i>: a review.

ABSTRACT: Ziziphi Spinosae Semen (ZSS) is the seeds of Ziziphus jujuba Mill. var. Spinosa (Bunge) Hu ex H. F. Chou, which has the effects of nourishing heart and liver, tranquilizing heart and tranquilizing mind. With the development of research on the metabolites of ZSS, more than 160 metabolites have been isolated from ZSS, including saponins, alkaloids, flavonoids, fatty acids, volatile oils, polysaccharides and proteins. The active metabolites of ZSS have regulatory effects on the nervous system, cardiovascular system, hematopoietic system, immune system and substance metabolism, and have various pharmacological effects such as anti-oxidation, anti-aging and anti-cancer. Although many traditional uses of ZSS have been clarified, the relationship between its structure and function r

SUBMITTER: Liu MH 

PROVIDER: S-EPMC11639084 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature