Modeling Grid Cell Distortions with a Grid Cell Calibration Mechanism.

ABSTRACT: The medial entorhinal cortex of rodents is known to contain grid cells that exhibit precise periodic firing patterns based on the animal's position, resulting in a distinct hexagonal pattern in space. These cells have been extensively studied due to their potential to unveil the navigational computations that occur within the mammalian brain and interesting phenomena such as so-called grid cell distortions have been observed. Previous neuronal models of grid cells assumed their firing fields were independent of environmental boundaries. However, more recent research has revealed that the grid pattern is, in fact, dependent on the environment's boundaries. When rodents are placed in nonsquare cages, the hexagonal pattern tends to become disrupted and adopts different shapes. We believe that

SUBMITTER: Strauß D 

PROVIDER: S-EPMC11639139 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature