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Clinical efficacy and safety of organ-sparing cystectomy: a systematic review and meta-analysis.


ABSTRACT:

Background

The clinical safety and efficacy of organ-sparing cystectomy (OSC) are subjects of ongoing debate, particularly concerning the potential increased risk of recurrence when retaining additional organs and its effectiveness in preserving sexual and urinary functions.

Methods

Adhering to the PRISMA 2020 statement and AMSTAR Guidelines, we conducted a systematic literature search up to February 2024 using PubMed, Embase, and Web of Science. The comparison focused on the clinical safety and effectiveness of OSC and standard radical cystectomy (SRC) in the treatment of bladder tumors. Our assessment covered several dimensions: Surgical safety outcomes (operation time, length of stay (LOS), estimated blood loss (EBL), and complications), oncological safety outcomes (recur

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11639212 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature