Effects of pharmacogenomics-guided treatment on medication adherence and the antidepressant switching rate in major depressive disorder.

ABSTRACT:

Background

In the treatment of depression, medication plays a crucial role. However, insufficient patient adherence to medication often results in unsatisfactory treatment outcomes, increasing both the recurrence and rehospitalization rates of depression, and consequently imposing a greater economic burden on the healthcare system.

Objectives

Our objective was to examine the impact of pharmacogenomic testing on medication adherence and antidepressant switching rates among individuals diagnosed with depression.

Methods

This retrospective cohort study encompassed patients diagnosed with depression who were admitted to the First Hospital of Hebei Medical University between April 2022 and September 2023. Patients were categorized into a pharmacogenomics-guided treatment (

SUBMITTER: Chen C 

PROVIDER: S-EPMC11639597 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature