Near-Wall Slow Flow Contributes to Wall Enhancement of Middle Cerebral Artery Bifurcation Aneurysms on Vessel Wall MRI.

ABSTRACT: Background: The mechanism of aneurysm wall enhancement (AWE) in middle cerebral artery (MCA) bifurcation aneurysms on vessel wall magnetic resonance imaging (VW-MRI) remains unclear. We aimed to explore the morphologically related hemodynamic mechanism for the AWE of MCA bifurcation aneurysms. Methods: Patients with unruptured MCA bifurcation aneurysms undergoing VW-MRI were enrolled. Logistic regression analyses were performed to determine the risk factors for AWE. Based on the results of retrospective analyses, bifurcation aneurysm silicone models with a specific aspect ratio (AR) were designed and underwent VW-MRI with different inlet velocities. Computational fluid dynamics (CFD) analyses were conducted on both silicone models and patients' aneurysms. Results: A to

SUBMITTER: Liu L 

PROVIDER: S-EPMC11639947 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature