Uterine Carcinosarcoma (UCS): A Literature Review and Survival Analysis from a Retrospective Cohort Study.

ABSTRACT:

Background/objectives

Uterine carcinosarcomas (UCSs) are rare and aggressive malignancies with limited epidemiological data. This study aims to evaluate the clinical and pathological features and prognostic factors of UCS in a retrospective cohort of 80 patients, contributing to improved management strategies.

Methods

We conducted a retrospective analysis of UCS cases treated from 1995 to 2024 at three institutions. Data on demographics, clinical features, histopathology, treatment, and outcomes were collected. Overall survival (OS) and prognostic factors were assessed using Kaplan-Meier and Cox proportional hazards regression analyses.

Results

The median age of patients was 66 years, with a median overall survival of 34.5 months. Disease recurrence occurred in 32.5%

SUBMITTER: Maiorano MFP 

PROVIDER: S-EPMC11640543 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature