Absolute depth-resolved optic axis measurement with catheter-based polarization sensitive optical coherence tomography.

ABSTRACT: Imaging depth-resolved birefringence and optic axis orientation with polarization sensitive optical coherence tomography (PS-OCT) unveils details of tissue structure and organization that can be of high pathophysiologic, mechanistic, and diagnostic value. For catheter-based PS-OCT, the dynamic rotation of the fiber optic probe, in addition to the polarization effects of the system components, complicates the reliable and robust reconstruction of the sample's optic axis orientation. Addressing this issue, we present a new method for the reconstruction of absolute depth-resolved optic axis orientation in catheter-based PS-OCT by using the intrinsic retardance of the protecting catheter sheath as a stable guide star signal. Throughout the paper, we rigorously inspect the retardance and optic

SUBMITTER: Masoumi S 

PROVIDER: S-EPMC11640563 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature