Near-infrared diffuse optical characterization of human thyroid using ultrasound-guided hybrid time-domain and diffuse correlation spectroscopies.

ABSTRACT: Thyroid vascularization and hemodynamics become altered in thyroid pathologies and could thus inform diagnostics, therapy planning, and follow-up. However, the current non-invasive monitoring methods available in clinics lack the necessary sensitivity and/or are impractical for large-scale deployment. As a step towards proposing a new modality, we applied the first platform, to our knowledge, designed to do simultaneous measurements of neck anatomy and thyroid microvascular hemodynamics and metabolism in a single probe placement, integrating state-of-the-art near-infrared spectroscopy techniques and clinical ultrasound. A rich dataset was formed with sixty-five subjects (forty-eight females), including eighteen healthy volunteers and forty-seven patients with thyroid nodules, characterizin

SUBMITTER: Fernandez Esteberena P 

PROVIDER: S-EPMC11640565 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature