Hepatoprotective, Lipid-Lowering and Antioxidant Effects of Mangaba Powder (<i>Hancornia speciosa</i>) Administered to Rats Fed a High-Fat Diet.

ABSTRACT: The aim of this study was to evaluate the potential effects of administering mangaba powder on liver function and somatic, oxidative and lipid metabolism parameters in rats fed a high-fat diet. Prepared mangaba powder has important amounts of phenolic compounds, vitamin C, dietary fiber and oligosaccharides. A total of 32 adult Wistar rats were initially randomized into two groups for the biological assay: normal-fat (NF, n = 16) and high-fat (HF, n = 16) diets for 21 days. These rats were subsequently subdivided into four groups: NF (n = 8), HF (n = 8), normal-fat diet with mangaba powder administration (NFMG, n = 8) and high-fat diet with mangaba powder administration (HFMG, n = 8). The treatment with mangaba powder (400 mg/kg) lasted an additional 28 days. Compared to the HF rats, the H

SUBMITTER: Silva BLA 

PROVIDER: S-EPMC11640672 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature