Colorectal Neoplasia Detection Rates in Lynch Syndrome.

ABSTRACT:

Background

The expected and optimal adenoma detection rate (ADR) is not well characterized in Lynch syndrome (LS). The aim of this study is to determine the ADR, the overall colorectal neoplasia detection rate (CNDR), proximal serrated detection rate (PSDR), and CRC detection rate (CRCDR) in an LS cohort.

Methods

A retrospective study was performed of individuals with LS who were evaluated at a single tertiary care center from May 2001 to September 2023 (n = 542). Data from procedure and pathology reports were collected along with relevant demographic, clinical history, and family history data. Fisher's exact test and the Kruskal-Wallis test were used to assess factors associated with colorectal neoplasia.

Results

Amongst 542 individuals with LS, 352 met the in

SUBMITTER: Mirda D 

PROVIDER: S-EPMC11640722 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature