Positive Effects of Argon Inhalation After Traumatic Brain Injury in Rats.

ABSTRACT: The noble gas argon is one of the most promising neuroprotective agents for hypoxic-reperfusion injuries of the brain. However, its effect on traumatic injuries has been insufficiently studied. The aim of this study was to analyze the effect of the triple inhalation of the argon-oxygen mixture Ar 70%/O₂ 30% on physical and neurological recovery and the degree of brain damage after traumatic brain injury and to investigate the possible molecular mechanisms of the neuroprotective effect. The experiments were performed in male Wistar rats. A controlled brain injury model was used to investigate the effects of argon treatment and the underlying molecular mechanisms. The results of the study showed that animals with craniocerebral injuries that were treated with argon inhalation exhi

SUBMITTER: Antonova VV 

PROVIDER: S-EPMC11640893 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature