Tunable elliptical cylinders for rotational mechanical studies of single DNA molecules.

ABSTRACT: The angular optical trap (AOT) is a powerful technique for measuring the DNA topology and rotational mechanics of fundamental biological processes. Realizing the full potential of the AOT requires rapid torsional control of these processes. However, existing AOT quartz cylinders are limited in their ability to meet the high rotation rate requirement while minimizing laser-induced photodamage. In this work, we present a trapping particle design to meet this challenge by creating small metamaterial elliptical cylinders with tunable trapping force and torque properties. The optical torque of these cylinders arises from their shape anisotropy, with their optical properties tuned via multilayered SiO₂ and Si₃N₄ deposition. We demonstrate that these cylinders can

SUBMITTER: Hong Y 

PROVIDER: S-EPMC11641005 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature