Long term efficacy and safety profile of dexamethasone intravitreal implant in retinal vein occlusions: a systematic review.

ABSTRACT:

Background/objective

Retinal vein occlusion (RVO) is a common, sight-threatening vascular disorder affecting individuals of all ages, with incidence increasing with age. Due to its complex, multifactorial nature, treating RVO remains a clinical challenge. Currently, treatment strategies include laser photocoagulation (especially for branch RVO), anti-VEGF therapies, and intravitreal corticosteroids. This systematic review (without meta-analysis) aimed to update the evidence on the efficacy and safety of the sustained-release intravitreal dexamethasone implant (DEX-i) in managing macular edema (ME) secondary to central and branch RVO.

Methods

A systematic review was conducted to assess current literature on DEX-i for ME secondary to RVO. Relevant studies were analyzed for out

SUBMITTER: Carnevali A 

PROVIDER: S-EPMC11641122 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature