20-Hydroxyecdysone Mediates Reproductive Diapause in Galeruca daurica via Ecdysone Receptor EcR and Nuclear Hormone Receptor HR3.

ABSTRACT: 20-hydroxyecdysone (20E) signaling plays an important role in regulating insect growth, development, and reproduction. However, the effect of 20E on reproductive diapause and its regulatory mechanisms have not been fully understood. Galeruca daurica is a new pest in the Inner Mongolia grasslands, and it aestivates in an obligatory reproductive diapause form. In this study, the complete open reading frame (ORF) sequence of the ecdysone receptor (EcR) was cloned from G. daurica. Application of 20E promoted the expression of EcR, nuclear hormone receptor (HR3), and vitellogenin (Vg), whereas it reduced the expression of fatty acid synthase (FAS) and lipid content, leading to delayed diapause entry in female adults. S

SUBMITTER: Li L 

PROVIDER: S-EPMC11641180 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature