MirSNPs as Potential Colorectal Cancer Biomarkers: A Systematic Review.

ABSTRACT: Colorectal cancer (CRC) is the third most common neoplasm in the world and the second with the highest mortality rate. Single nucleotide polymorphisms (SNPs) in microRNA (miRNA) genes known as mirSNPs may be related to dysregulated miRNA expression in several neoplasms. This systematic review aims to investigate studies that investigate SNPs located in regions of miRNA genes that influence their expression and are associated with CRC, as well as their potential as biomarkers for the disease, based on the available literature. For this, searches were performed in public databases, including MEDLINE/PubMed, Embase, Web of Science, and Scopus. The rigorous review of the PRISMA 2020 guidelines and the methodological quality of these studies was assessed using the Newcastle-Ottawa scale and the

SUBMITTER: Alves Dos Santos K 

PROVIDER: S-EPMC11641632 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature