A Comparative Analysis of the Impact of Severe Acute Respiratory Syndrome Coronavirus 2 Infection on the Performance of Clinical Decision-Making Algorithms for Pulmonary Embolism.

ABSTRACT: Background/Objectives: This study aimed to compare the diagnostic accuracy of the Wells and Geneva scores using a 500 ng/mL D-dimer cutoff, as well as the age-adjusted D-dimer (AADD), YEARS, and pulmonary embolism graduated D-dimer (PEGeD) algorithms, in patients with and without COVID-19. Various D-dimer cutoffs were also evaluated. Methods: This retrospective study included emergency department patients who underwent computed tomography pulmonary angiography (CTPA) for suspected pulmonary embolism (PE). The diagnostic performances of clinical prediction algorithms were compared between COVID-19-positive and -negative groups. Results: We analyzed data from 1423 patients; the PE and COVID-19 positivity rates were 7.3% and 69.9%, respectively. In COVID-19-positive patie

SUBMITTER: Eksioglu M 

PROVIDER: S-EPMC11642087 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature