Neural divergence between individuals with and without minor depression during dynamic emotion processing: a movie-fMRI Study.

ABSTRACT: Research on the neuropathological mechanisms underlying minor depression (MD), particularly in individuals with a history of recurrent minor depressive episodes, is very limited. This study focuses on the abnormality in processing real-life emotional stimuli among individuals with MD. Thirty-two individuals with MD and 31 normal controls (NC) were recruited and underwent comprehensive clinical interview, cognitive assessment, and magnetic resonance imaging (MRI) scans. During functional MRI scanning, subjects watched positive, negative, and neutral emotional movie clips. We used the inter-subject correlation and inter-subject functional connectivity analysis to investigate the neural differentiation between MD and NC during film viewing. The relationships between neural differentiation, sy

SUBMITTER: Zhang M 

PROVIDER: S-EPMC11642607 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature