Mesoscale functional architecture in medial posterior parietal cortex.

ABSTRACT: The posterior parietal cortex (PPC) in mice has various functions including multisensory integration^1-3, vision-guided behaviors^4-6, working memory^7-13, and posture control^14,15. However, an integrated understanding of these functions and their cortical localizations in and around the PPC and higher visual areas (HVAs), has not been completely elucidated. Here we simultaneously imaged the activity of thousands of neurons within a 3 × 3 mm² field-of-view, including eight cortical areas around the PPC, during behavior with a two-photon mesoscope¹⁶. Mice performed both a vision-guided task and a choice history-dependent task, and the imaging results revealed distinct, localized, behavior-related functions of two m

SUBMITTER: Hira R 

PROVIDER: S-EPMC11642780 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature