Development and application of species ID and insecticide resistance assays, for monitoring sand fly Leishmania vectors in the Mediterranean basin and in the Middle East.

ABSTRACT:

Background

Development of insecticide resistance (IR) in sand fly populations is an issue of public health concern, threatening leishmaniasis mitigation efforts by insecticide-based vector control. There is a major knowledge gap in the IR status of wild populations worldwide, possibly attributed to the unavailability of specialized tools, such as bioassay protocols, species baseline susceptibility to insecticides and molecular markers, to monitor such phenomena in sand flies.

Methodology/principal findings

Sand fly populations from (semi-)rural regions of Greece, Turkey and Iran were sampled and identified to species, showing populations' structure in accordance with previously reported data. Genotyping of known pyrethroid resistance-associated loci revealed the occurrence o

SUBMITTER: Balaska S 

PROVIDER: S-EPMC11642961 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature