Ligand-to-Metal Ratio Governs Radical-Scavenging Ability of Malate-Stabilised Ceria Nanoparticles.

ABSTRACT: Cerium dioxide sols stabilised with L-malic acid were shown to exhibit significant antioxidant activity towards alkyl peroxyl radicals in the range of ligand:CeO₂ molar ratios of 0.2-1 (0.2:1, 0.4:1, 0.5:1, 0.6:1, 0.8:1 and 1:1). The antioxidant activity of cerium dioxide nanoparticles greatly depended on L-malic acid content and increased by 8 times when the ligand:CeO₂ molar ratio increased from 0.2:1 to 0.4:1. An estimate of the ligand:CeO₂ molar ratio required to ensure complete surface coverage of CeO₂ nanoparticles with malate anions resulted in a value of 0.2. Aggregation degree of CeO₂ nanoparticles depends on the ligand:CeO₂ molar ratio. In the range of ligand:CeO₂ molar ratios 0.2-0.4, the size of aggreg

SUBMITTER: Filippova AD 

PROVIDER: S-EPMC11643014 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature