Development and Application of a Robust Imine-Based Covalent Organic Framework for Stir Bar Sorptive Extraction of Estrogens in Environmental Water.

ABSTRACT: A covalent organic framework (COF) based on imine was synthesized using 2,5-dihexoxyterephthalaldehyde (DHT) and 1,3,5-tris(4-aminophenyl) benzene (TAPB) as starting materials. The TAPB-DHT-COF exhibited satisfactory chemical stability, making it a promising adsorbing material for stir bar sorptive extraction (SBSE) of four estrogens, including estrone (E1), β-estradiol (E2), hexestrol (HES), and mestranol (MeEE2), in ambient water samples. The extracted analytes were subsequently analyzed using a high-performance liquid chromatography-diode array detector (HPLC-DAD). A series of parameters affecting the SBSE process, such as solution pH, ionic strength, extraction time, and desorption solvent, were investigated by the controlled variable method. Under optimal conditions, the limit of dete

SUBMITTER: Sun J 

PROVIDER: S-EPMC11643056 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature