Long Sleep Duration, Cognitive Performance, and the Moderating Role of Depression: A Cross-Sectional Analysis in the Framingham Heart Study.

ABSTRACT:

Introduction

We investigated whether depression modified the associations between sleep duration and cognitive performance.

Methods

Multivariable linear regression models examined the associations between sleep duration and cognition in 1,853 dementia- and stroke-free participants from the Framingham Heart Study. Participants were categorized in four groups: no depressive symptoms, no antidepressants; depressive symptoms without antidepressants use; antidepressant use without depressive symptoms; both depressive symptoms and antidepressant use.

Results

Long sleep was associated with reduced overall cognitive function. Strong associations between sleep duration and cognitive performance were found in individuals with depressive symptoms, regardless of antidepressant us

SUBMITTER: Young VM 

PROVIDER: S-EPMC11643162 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature