The oral microbiome and all-cause mortality in the US population.

ABSTRACT:

Importance

Poor oral health, including periodontal disease, is associated with oral microbiome changes and increased mortality risk. However, no large studies have evaluated whether the oral microbiome is directly associated with mortality.

Objective

To evaluate whether measures of the oral microbiome is prospectively associated with all-cause mortality.

Design

A cross-sectional survey with samples collected from 2009-2012 and mortality linkage to the restricted-use National Death Index (NDI) through 2019.

Setting

The National Health and Nutrition Examination Survey (NHANES) 2009-2012, a multistage probability sample of the US population.

Participants

NHANES participants 20- to 69-years-old who were eligible for linkage to the NDI and provided oral rinse

SUBMITTER: Vogtmann E 

PROVIDER: S-EPMC11643182 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature