Cardiometabolic Outcomes in Idiopathic Intracranial Hypertension: An International Matched-Cohort Study.

ABSTRACT:

Introduction

Idiopathic intracranial hypertension (IIH) has been traditionally viewed as a neuro-ophthalmic disorder, yet emerging evidence suggests broader systemic implications. Our study investigates the cardiometabolic outcomes associated with IIH through a comprehensive matched-cohort analysis.

Methods

We conducted a retrospective analysis of electronic health records from 2009 to 2024. We compared IIH patients with matched controls using propensity score matching based on age, sex, race, ethnicity, and baseline BMI. Cardiovascular and metabolic outcomes were assessed over a ten-year follow-up period, with additional stratified analyses comparing obese and non-obese subgroups.

Results

IIH patients demonstrated significantly increased risks of ischemic stroke/TIA

SUBMITTER: Azzam AY 

PROVIDER: S-EPMC11643231 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature